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| 25.09.2021 | 15:00 | Turgutluspor | - | Çorum FK | 0:0 (0:0) | |
| 26.09.2021 | 12:00 | Adıyamanspor | - | Hekimoğlu Trabzon | 0:1 (0:0) | |
| 14:30 | Etimesgut Belediyespor | - | Sivas Belediyespor | 0:0 (0:0) | ||
| 14:30 | Kahramanmaraşspor | - | Bayburt İl Özel İdare | 0:1 (0:1) | ||
| 14:30 | Niğde Anadolu FK | - | Inegölspor | 1:5 (0:3) | ||
| 15:00 | Ergene Velimeşe | - | Vanspor FK | 1:2 (1:1) | ||
| 15:00 | Serik Belediyespor | - | Sarıyer SK | 2:1 (2:1) | ||
| 17:00 | Sakaryaspor | - | Bodrumspor | 1:0 (1:0) | ||
| 18:00 | Afjet Afyonspor | - | Ankaraspor | 2:1 (0:0) | ||
| 18:00 | Diyarbekirspor | - | Somaspor | 3:1 (1:1) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hekimoğlu Trabzon | 4 | 3 | 1 | 0 | 10:2 | 8 | 10 |
| 2 |
|
Sivas Belediyespor | 4 | 3 | 1 | 0 | 9:1 | 8 | 10 |
| 3 |
|
Vanspor FK | 4 | 3 | 1 | 0 | 9:5 | 4 | 10 |
| 4 |
|
Bayburt İl Özel İdare | 4 | 3 | 1 | 0 | 6:2 | 4 | 10 |
| 5 |
|
Bodrumspor | 4 | 3 | 0 | 1 | 7:2 | 5 | 9 |
| 6 |
|
Sakaryaspor | 4 | 2 | 2 | 0 | 4:1 | 3 | 8 |
| 7 |
|
Ankaraspor | 4 | 2 | 1 | 1 | 11:4 | 7 | 7 |
| 8 |
|
Etimesgut Belediyespor | 4 | 2 | 1 | 1 | 7:5 | 2 | 7 |
| 9 |
|
Somaspor | 4 | 2 | 1 | 1 | 7:6 | 1 | 7 |
| 10 |
|
Çorum FK | 4 | 1 | 3 | 0 | 5:1 | 4 | 6 |
| 11 |
|
Serik Belediyespor | 4 | 2 | 0 | 2 | 5:7 | -2 | 6 |
| 12 |
|
Inegölspor | 4 | 1 | 2 | 1 | 6:4 | 2 | 5 |
| 13 |
|
Afjet Afyonspor | 4 | 1 | 2 | 1 | 8:8 | 0 | 5 |
| 14 |
|
Diyarbekirspor | 4 | 1 | 1 | 2 | 5:7 | -2 | 4 |
| 15 |
|
Sarıyer SK | 4 | 1 | 1 | 2 | 4:6 | -2 | 4 |
| 16 |
|
Turgutluspor | 4 | 0 | 1 | 3 | 3:6 | -3 | 1 |
| 17 |
|
Ergene Velimeşe | 4 | 0 | 1 | 3 | 2:10 | -8 | 1 |
| 18 |
|
Adıyamanspor | 4 | 0 | 0 | 4 | 2:11 | -9 | 0 |
|
Kahramanmaraşspor | 4 | 0 | 0 | 4 | 2:11 | -9 | 0 | |
| 20 |
|
Niğde Anadolu FK | 4 | 0 | 0 | 4 | 1:14 | -13 | 0 |
| Ascenso | |
| Playoff | |
| Descenso |
