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| 01.10.2010 | 18:00 | Metalurg Zaporizhya | - | Dnipro Dnipropetrovsk | 0:3 (0:1) | |
| 02.10.2010 | 12:00 | FK Illichivets | - | FK Obolon | 1:0 (0:0) | |
| 14:00 | Zorya Lugansk | - | Vorskla Poltava | 1:1 (0:0) | ||
| 15:00 | Arsenal Kiev | - | Metalurh Donetsk | 3:1 (1:0) | ||
| 18:00 | Volyn Lutsk | - | Tavriya Simferopol (1958-2014) | 2:2 (1:0) | ||
| 03.10.2010 | 13:00 | PFK Sevastopol | - | FK Krivbas (old) | 2:2 (1:1) | |
| 15:00 | Karpaty Lviv | - | Metalist Kharkiv | 0:1 (0:0) | ||
| 18:00 | Shakhtar Donetsk | - | Dinamo Kiev | 2:0 (0:0) |
| » Clasificación | En casa | Fuera de casa | 1.ª vuelta | 2.ª vuelta |
| # | Equipo | P | V | E | D | Goles | DG | Pun. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Shakhtar Donetsk | 12 | 10 | 1 | 1 | 23:5 | 18 | 31 |
| 2 |
|
Dinamo Kiev | 12 | 8 | 2 | 2 | 19:12 | 7 | 26 |
| 3 |
|
Dnipro Dnipropetrovsk | 12 | 7 | 2 | 3 | 20:7 | 13 | 23 |
| 4 |
|
Metalist Kharkiv | 12 | 7 | 1 | 4 | 19:11 | 8 | 22 |
| 5 |
|
Karpaty Lviv | 12 | 6 | 2 | 4 | 15:12 | 3 | 20 |
| 6 |
|
Vorskla Poltava | 12 | 5 | 3 | 4 | 15:13 | 2 | 18 |
| 7 |
|
Metalurh Donetsk | 12 | 5 | 3 | 4 | 16:15 | 1 | 18 |
| 8 |
|
Arsenal Kiev | 12 | 5 | 2 | 5 | 15:14 | 1 | 17 |
| 9 |
|
FK Krivbas (old) | 12 | 3 | 6 | 3 | 13:16 | -3 | 15 |
| 10 |
|
Volyn Lutsk | 12 | 4 | 3 | 5 | 9:13 | -4 | 15 |
| 11 |
|
Tavriya Simferopol (1958-2014) | 12 | 4 | 2 | 6 | 18:19 | -1 | 14 |
| 12 |
|
FK Illichivets | 12 | 3 | 4 | 5 | 17:21 | -4 | 13 |
| 13 |
|
Zorya Lugansk | 12 | 2 | 5 | 5 | 13:18 | -5 | 11 |
| 14 |
|
FK Obolon | 12 | 3 | 2 | 7 | 7:17 | -10 | 11 |
| 15 |
|
PFK Sevastopol | 12 | 2 | 4 | 6 | 8:19 | -11 | 10 |
| 16 |
|
Metalurg Zaporizhya | 12 | 0 | 2 | 10 | 4:19 | -15 | 2 |
| Champions League | |
| CL Ronda previa | |
| Europa League | |
| Descenso |
