| 2. Jornada | 20.03.2022 | Aris Saloniki | - | Panathinaikos | 0:0 |  |
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| 3. Jornada | 03.04.2022 | Panathinaikos | - | PAOK Saloniki | 2:1 | ||||
| 4. Jornada | 10.04.2022 | PAS Giannina | - | Panathinaikos | 0:0 | ||||
| 5. Jornada | 17.04.2022 | Panathinaikos | - | Olympiacos | 1:0 | ||||
| 6. Jornada | 01.05.2022 | Panathinaikos | - | Aris Saloniki | 1:0 | ||||
| 7. Jornada | 08.05.2022 | AEK Athen | - | Panathinaikos | 0:0 | ||||
| 8. Jornada | 11.05.2022 | Olympiacos | - | Panathinaikos | 1:2 | |
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| 9. Jornada | 14.05.2022 | Panathinaikos | - | PAS Giannina | 4:0 |
Italia