| 1. Jornada | 24.07.2021 | Dinamo Stavropol | - | FK Mashuk KMV | 1:1 |  |
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| 3. Jornada | 06.08.2021 | FK Yessentuki | - | FK Mashuk KMV | 0:2 | ||||
| 4. Jornada | 15.08.2021 | FK Mashuk KMV | - | FK Biolog Novokubansk | 2:0 | ||||
| 5. Jornada | 20.08.2021 | FK Legion Dynamo Makhachkala | - | FK Mashuk KMV | 2:2 | ||||
| 7. Jornada | 04.09.2021 | FK Mashuk KMV | - | Spartak Nalchik | 1:2 | ||||
| 9. Jornada | 13.09.2021 | FK Mashuk KMV | - | Anzhi Makhachkala | 0:3 | ||||
| 10. Jornada | 18.09.2021 | FK Druzhba | - | FK Mashuk KMV | 1:1 | ||||
| 11. Jornada | 26.09.2021 | FK Mashuk KMV | - | Alania-2 Vladikavkaz | 4:1 |  |
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| 12. Jornada | 03.10.2021 | Kuban-Holding Pavlovskaya | - | FK Mashuk KMV | 1:0 | |
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| 13. Jornada | 10.10.2021 | FK Mashuk KMV | - | Forte Taganrog | 0:2 | |
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| 15. Jornada | 23.10.2021 | FK Mashuk KMV | - | Rotor-2 Volgograd | 1:1 | ||||
| 19. Jornada | 27.10.2021 | FK Mashuk KMV | - | FK Yessentuki | 7:0 | ||||
| 16. Jornada | 01.11.2021 | FK Tuapse | - | FK Mashuk KMV | 3:0 | |
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| 17. Jornada | 06.11.2021 | FK Mashuk KMV | - | FK SKA Rostov | 0:2 | ||||
| 18. Jornada | 13.11.2021 | Chernomorets Novorossisk | - | FK Mashuk KMV | 3:2 | |
Rusia