| 1. Jornada | 23.02.2025 | St. Louis City SC | - | Colorado Rapids | 0:0 | ||||
| 2. Jornada | 02.03.2025 | San Diego FC | - | St. Louis City SC | 0:0 | ||||
| 3. Jornada | 10.03.2025 | Los Angeles Galaxy | - | St. Louis City SC | 0:3 | ||||
| 4. Jornada | 16.03.2025 | St. Louis City SC | - | Seattle Sounders | 1:0 | ||||
| 5. Jornada | 23.03.2025 | Philadelphia Union | - | St. Louis City SC | 1:0 |  |
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| 6. Jornada | 30.03.2025 | St. Louis City SC | - | Austin FC | 0:1 | ||||
| 7. Jornada | 06.04.2025 | Sporting Kansas City | - | St. Louis City SC | 2:0 | ||||
| 8. Jornada | 14.04.2025 | St. Louis City SC | - | Columbus Crew | 1:2 | ||||
| 9. Jornada | 20.04.2025 | St. Louis City SC | - | Vancouver Whitecaps | 0:0 | ||||
| 10. Jornada | 28.04.2025 | Los Angeles FC | - | St. Louis City SC | 2:2 |  |
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| 17. Jornada | 31.05.2025 | St. Louis City SC | - | San Jose Earthquakes | 2:1 | ||||
| 18. Jornada | 09.06.2025 | Portland Timbers | - | St. Louis City SC | 2:1 | ||||
| 18. Jornada | 14.06.2025 | St. Louis City SC | - | Los Angeles Galaxy | 3:3 | ||||
| 19. Jornada | 26.06.2025 | St. Louis City SC | - | Orlando City | 2:4 | ||||
| 20. Jornada | 29.06.2025 | Houston Dynamo | - | St. Louis City SC | 1:0 |
Alemania