| 1. Jornada | 16.07.2022 | Sportivo Ameliano | - | Libertad | 2:0 |  |
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| 2. Jornada | 20.07.2022 | Libertad | - | Club Olimpia | 4:2 | ||||
| 7. Jornada | 21.08.2022 | Club Nacional | - | Libertad | 0:2 | |
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| 9. Jornada | 05.09.2022 | Cerro Porteño | - | Libertad | 1:0 | |
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| 10. Jornada | 10.09.2022 | Guaireña FC | - | Libertad | 4:0 | ||||
| 14. Jornada | 03.10.2022 | Libertad | - | General Caballero DJLM | 1:0 | ||||
| 15. Jornada | 06.10.2022 | Resistencia SC | - | Libertad | 1:0 |  |
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| 13. Jornada | 13.10.2022 | Club Olimpia | - | Libertad | 1:0 |
Paraguay