| 1. Jornada | 11.01.2021 | CF Pachuca [Sub 20] | - | FC Juárez [Sub 20] | 2:0 | ||||
| 2. Jornada | 18.01.2021 | Club León [Sub 20] | - | CF Pachuca [Sub 20] | 0:3 |  |
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| 5. Jornada | 04.02.2021 | Gallos Blancos [Sub 20] | - | CF Pachuca [Sub 20] | 1:2 | |
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| 6. Jornada | 15.02.2021 | CF Pachuca [Sub 20] | - | Atlas Guadalajara [Sub 20] | 3:0 | ||||
| 9. Jornada | 04.03.2021 | Club Necaxa [Sub 20] | - | CF Pachuca [Sub 20] | 1:1 | ||||
| 10. Jornada | 08.03.2021 | CF Pachuca [Sub 20] | - | Club Tijuana [Sub 20] | 3:2 | ||||
| 11. Jornada | 14.03.2021 | Deportivo Toluca [Sub 20] | - | CF Pachuca [Sub 20] | 2:1 | ||||
| 12. Jornada | 18.03.2021 | CF Pachuca [Sub 20] | - | UANL Tigres [Sub 20] | 2:1 | |
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| 13. Jornada | 04.04.2021 | Pumas UNAM [Sub 20] | - | CF Pachuca [Sub 20] | 4:4 | |
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| 3. Jornada | 07.04.2021 | CF Pachuca [Sub 20] | - | Cruz Azul [Sub 20] | 0:0 | ||||
| 16. Jornada | 26.04.2021 | CF Pachuca [Sub 20] | - | Santos Laguna [Sub 20] | 3:1 |
México