| 1. Jornada | 23.07.2018 | Santos Laguna | - | Lobos BUAP | 2:1 |  |
|||
| 2. Jornada | 29.07.2018 | Lobos BUAP | - | CD Veracruz | 2:0 | ||||
| 3. Jornada | 05.08.2018 | Club Necaxa | - | Lobos BUAP | 1:0 | ||||
| 4. Jornada | 12.08.2018 | Lobos BUAP | - | Atlas Guadalajara | 0:0 | ||||
| 5. Jornada | 19.08.2018 | CF Pachuca | - | Lobos BUAP | 3:0 | ||||
| 6. Jornada | 23.08.2018 | Lobos BUAP | - | CF Monterrey | 1:2 | ||||
| 7. Jornada | 26.08.2018 | Gallos Blancos | - | Lobos BUAP | 2:0 | ||||
| 8. Jornada | 02.09.2018 | Lobos BUAP | - | CF América | 0:2 | ||||
| 9. Jornada | 16.09.2018 | Pumas UNAM | - | Lobos BUAP | 4:2 | ||||
| 10. Jornada | 23.09.2018 | Club León | - | Lobos BUAP | 0:1 | ||||
| 11. Jornada | 30.09.2018 | Lobos BUAP | - | Monarcas Morelia | 3:1 | ||||
| 12. Jornada | 08.10.2018 | Puebla FC | - | Lobos BUAP | 2:2 |  |
|||
| 13. Jornada | 21.10.2018 | Lobos BUAP | - | Deportivo Guadalajara | 1:1 | ||||
| 14. Jornada | 28.10.2018 | UANL Tigres | - | Lobos BUAP | 2:2 | ||||
| 15. Jornada | 04.11.2018 | Lobos BUAP | - | Club Tijuana | 3:1 | |
|||
| 16. Jornada | 11.11.2018 | Cruz Azul | - | Lobos BUAP | 2:1 | ||||
| 17. Jornada | 25.11.2018 | Lobos BUAP | - | Deportivo Toluca | 2:0 |  |
Chile
España 