| 1. Jornada | 29.01.2023 | Guaireña FC | - | Club Nacional | 1:3 | ||||
| 4. Jornada | 18.02.2023 | Guaireña FC | - | Cerro Porteño | 0:2 | ||||
| 6. Jornada | 03.03.2023 | Guaireña FC | - | General Caballero DJLM | 0:0 | ||||
| 7. Jornada | 11.03.2023 | Libertad | - | Guaireña FC | 2:0 | ||||
| 8. Jornada | 18.03.2023 | Guaireña FC | - | Sportivo Ameliano | 0:1 | ||||
| 9. Jornada | 24.03.2023 | Guaraní | - | Guaireña FC | 1:1 | ||||
| 10. Jornada | 02.04.2023 | Guaireña FC | - | Resistencia SC | 1:3 | ||||
| 11. Jornada | 09.04.2023 | Sportivo Luqueño | - | Guaireña FC | 0:0 | ||||
| 12. Jornada | 12.04.2023 | Club Nacional | - | Guaireña FC | 2:2 | ||||
| 13. Jornada | 15.04.2023 | Guaireña FC | - | Tacuary | 0:1 | ||||
| 14. Jornada | 22.04.2023 | Sportivo Trinidense | - | Guaireña FC | 1:0 | ||||
| 22. Jornada | 09.06.2023 | Guaireña FC | - | Sportivo Luqueño | 0:2 |
Paraguay