| 6. Jornada | 21.08.2021 | CF Monterrey [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 1:1 | ||||
| 7. Jornada | 28.08.2021 | Club Tijuana [Sub 20] | - | CF Monterrey [Sub 20] | 1:0 | ||||
| 10. Jornada | 26.09.2021 | Santos Laguna [Sub 20] | - | CF Monterrey [Sub 20] | 4:1 | ||||
| 15. Jornada | 23.10.2021 | CF Monterrey [Sub 20] | - | Club Necaxa [Sub 20] | 5:1 | ||||
| 16. Jornada | 31.10.2021 | Atlético San Luis [Sub 20] | - | CF Monterrey [Sub 20] | 3:1 | ||||
| 17. Jornada | 06.11.2021 | CF América [Sub 20] | - | CF Monterrey [Sub 20] | 2:0 |
México