| 1. Jornada | 31.07.2022 | Montevideo Wanderers | - | River Plate | 1:2 |  |
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| 2. Jornada | 06.08.2022 | Cerro Largo | - | Montevideo Wanderers | 1:1 | ||||
| 6. Jornada | 20.08.2022 | Nacional | - | Montevideo Wanderers | 2:0 | |
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| 5. Jornada | 27.08.2022 | Montevideo Wanderers | - | Albion | 0:0 | ||||
| 4. Jornada | 03.09.2022 | Defensor Sporting | - | Montevideo Wanderers | 1:0 | |
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| 7. Jornada | 10.09.2022 | Montevideo Wanderers | - | Danubio | 0:3 | ||||
| 8. Jornada | 13.09.2022 | Deportivo Maldonado | - | Montevideo Wanderers | 1:0 | ||||
| 9. Jornada | 18.09.2022 | Montevideo Wanderers | - | Rentistas | 1:0 | ||||
| 10. Jornada | 24.09.2022 | Liverpool | - | Montevideo Wanderers | 1:1 | |
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| 11. Jornada | 03.10.2022 | Montevideo Wanderers | - | Peñarol | 0:2 | ||||
| 12. Jornada | 09.10.2022 | Montevideo City Torque | - | Montevideo Wanderers | 1:0 | ||||
| 14. Jornada | 17.10.2022 | Montevideo Wanderers | - | Plaza Colonia | 2:1 | ||||
| 15. Jornada | 24.10.2022 | Boston River | - | Montevideo Wanderers | 2:2 |
Chile