| 4. Jornada | 28.08.2021 | Caen (CFA) | - | US Granvillaise | 1:1 | ||||
| 5. Jornada | 04.09.2021 | Blois Foot 41 | - | Caen (CFA) | 2:1 | ||||
| 6. Jornada | 11.09.2021 | Caen (CFA) | - | SO Romorantin | 0:0 | ||||
| 8. Jornada | 25.09.2021 | Caen (CFA) | - | FC Rouen 1899 | 2:5 | ||||
| 9. Jornada | 09.10.2021 | Guingamp (CFA) | - | Caen (CFA) | 1:1 |  |
|||
| 10. Jornada | 23.10.2021 | Caen (CFA) | - | AS Vitré | 1:0 | ||||
| 12. Jornada | 20.11.2021 | Caen (CFA) | - | FC Versailles | 1:0 |  |
|||
| 14. Jornada | 11.12.2021 | Caen (CFA) | - | US Saint-Malo | 0:0 | ||||
| 17. Jornada | 05.02.2022 | Caen (CFA) | - | St-Pryvé St-Hilaire | 1:4 | ||||
| 18. Jornada | 12.02.2022 | US Granvillaise | - | Caen (CFA) | 1:1 | ||||
| 19. Jornada | 19.02.2022 | Caen (CFA) | - | Blois Foot 41 | 3:2 | ||||
| 20. Jornada | 05.03.2022 | SO Romorantin | - | Caen (CFA) | 0:1 | ||||
| 21. Jornada | 12.03.2022 | Caen (CFA) | - | Lorient (CFA) | 1:3 | ||||
| 23. Jornada | 26.03.2022 | Caen (CFA) | - | Guingamp (CFA) | 0:2 | ||||
| 24. Jornada | 09.04.2022 | AS Vitré | - | Caen (CFA) | 2:0 | |
|||
| 27. Jornada | 30.04.2022 | Caen (CFA) | - | C'Chartres Football | 3:0 |
Francia