| 3. Jornada | 19.03.2022 | MFK Zemplín Michalovce | - | Zlaté Moravce | 1:0 | ||||
| 4. Jornada | 02.04.2022 | MFK Zemplín Michalovce | - | FK Pohronie | 1:0 | ||||
| 5. Jornada | 08.04.2022 | Tatran Liptovský Mikuláš | - | MFK Zemplín Michalovce | 3:1 | ||||
| 6. Jornada | 18.04.2022 | Zlaté Moravce | - | MFK Zemplín Michalovce | 1:1 | ||||
| 7. Jornada | 23.04.2022 | MFK Zemplín Michalovce | - | FK Senica | 1:0 | ||||
| 10. Jornada | 21.05.2022 | AS Trenčín | - | MFK Zemplín Michalovce | 2:2 |
Eslovaquia