| 1. Jornada | 03.04.2005 | Columbus Crew | - | Los Angeles Galaxy | 3:0 | ||||
| 1. Jornada | 10.04.2005 | New England Revolution | - | Columbus Crew | 3:0 | ||||
| 1. Jornada | 16.04.2005 | Columbus Crew | - | D.C. United | 1:0 |  |
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| 3. Jornada | 19.06.2005 | MetroStars | - | Columbus Crew | 3:2 | ||||
| 3. Jornada | 23.06.2005 | Columbus Crew | - | New England Revolution | 1:3 | ||||
| 4. Jornada | 03.07.2005 | Columbus Crew | - | D.C. United | 0:1 | ||||
| 4. Jornada | 10.07.2005 | Columbus Crew | - | San Jose Earthquakes | 1:2 | ||||
| 4. Jornada | 16.07.2005 | Chicago Fire | - | Columbus Crew | 1:1 | ||||
| 4. Jornada | 21.07.2005 | Columbus Crew | - | MetroStars | 1:0 | |
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| 4. Jornada | 24.07.2005 | Columbus Crew | - | Kansas City Wizards | 2:0 | ||||
| 5. Jornada | 07.08.2005 | San Jose Earthquakes | - | Columbus Crew | 2:1 | |
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| 5. Jornada | 27.08.2005 | Kansas City Wizards | - | Columbus Crew | 0:1 | ||||
| 6. Jornada | 04.09.2005 | CD Chivas | - | Columbus Crew | 0:3 | ||||
| 6. Jornada | 11.09.2005 | New England Revolution | - | Columbus Crew | 3:1 | ||||
| 7. Jornada | 06.10.2005 | FC Dallas | - | Columbus Crew | 2:1 |  |
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| 7. Jornada | 09.10.2005 | Chicago Fire | - | Columbus Crew | 1:2 | |
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| 7. Jornada | 16.10.2005 | D.C. United | - | Columbus Crew | 2:2 |
Estados Unidos