| 1. Jornada | 19.03.2022 | Panetolikos | - | Lamia | 1:2 | ||||
| 2. Jornada | 02.04.2022 | Apollon Smyrnis | - | Panetolikos | 1:0 | ||||
| 3. Jornada | 09.04.2022 | Panetolikos | - | Atromitos | 2:3 | ||||
| 4. Jornada | 16.04.2022 | Panetolikos | - | Asteras Tripolis | 0:0 | ||||
| 5. Jornada | 30.04.2022 | OFI Heraklion | - | Panetolikos | 0:1 | ||||
| 6. Jornada | 07.05.2022 | Panetolikos | - | Volos NFC | 0:0 | ||||
| 7. Jornada | 15.05.2022 | Ionikos Nikea | - | Panetolikos | 3:1 |  |
Honduras