| 5. Jornada | 21.02.2010 | Tacuary | - | Club Rubio Ñu | 0:1 | ||||
| 6. Jornada | 28.02.2010 | Tacuary | - | Sportivo Trinidense | 2:0 | ||||
| 7. Jornada | 06.03.2010 | Sportivo Luqueño | - | Tacuary | 3:3 |  |
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| 8. Jornada | 12.03.2010 | Tacuary | - | Sol de América | 1:1 | |
 |
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| 9. Jornada | 24.03.2010 | Club Nacional | - | Tacuary | 4:0 | ||||
| 11. Jornada | 28.03.2010 | Sport Colombia | - | Tacuary | 0:0 | ||||
| 12. Jornada | 05.04.2010 | Cerro Porteño | - | Tacuary | 1:0 | ||||
| 13. Jornada | 10.04.2010 | Tacuary | - | Club Olimpia | 0:4 |  |
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| 15. Jornada | 18.04.2010 | Tacuary | - | Guaraní | 1:4 | ||||
| 14. Jornada | 22.04.2010 | Libertad | - | Tacuary | 0:0 | ||||
| 16. Jornada | 25.04.2010 | Club Rubio Ñu | - | Tacuary | 3:1 | |
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| 17. Jornada | 02.05.2010 | Sportivo Trinidense | - | Tacuary | 0:1 | ||||
| 18. Jornada | 08.05.2010 | Tacuary | - | Sportivo Luqueño | 1:2 | ||||
| 19. Jornada | 12.05.2010 | Sol de América | - | Tacuary | 1:0 | ||||
| 21. Jornada | 22.05.2010 | 3 de Febrero | - | Tacuary | 1:0 | |
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| 22. Jornada | 28.05.2010 | Tacuary | - | Sport Colombia | 2:2 | |
Paraguay