| 3. Jornada | 15.07.2022 | Puebla FC [Sub 20] | - | Club León [Sub 20] | 3:1 | ||||
| 4. Jornada | 23.07.2022 | Cruz Azul [Sub 20] | - | Puebla FC [Sub 20] | 0:0 |  |
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| 6. Jornada | 30.07.2022 | Puebla FC [Sub 20] | - | Atlético San Luis [Sub 20] | 2:3 | ||||
| 16. Jornada | 02.08.2022 | Deportivo Toluca [Sub 20] | - | Puebla FC [Sub 20] | 1:2 | ||||
| 7. Jornada | 06.08.2022 | Puebla FC [Sub 20] | - | Pumas UNAM [Sub 20] | 1:2 | |
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| 13. Jornada | 07.09.2022 | Puebla FC [Sub 20] | - | CF Pachuca [Sub 20] | 1:2 | |
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| 15. Jornada | 16.09.2022 | Puebla FC [Sub 20] | - | UANL Tigres [Sub 20] | 1:1 |
México