| 1. Jornada | 22.01.2019 | San Lorenzo | - | River Plate | 1:0 | ||||
| 2. Jornada | 27.01.2019 | Club Olimpia | - | San Lorenzo | 2:0 | ||||
| 3. Jornada | 03.02.2019 | San Lorenzo | - | Club Nacional | 1:0 | ||||
| 4. Jornada | 07.02.2019 | San Lorenzo | - | Guaraní | 1:3 | ||||
| 5. Jornada | 11.02.2019 | Sportivo Luqueño | - | San Lorenzo | 0:3 |  |
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| 7. Jornada | 22.02.2019 | Sol de América | - | San Lorenzo | 1:6 | ||||
| 8. Jornada | 26.02.2019 | San Lorenzo | - | Cerro Porteño | 2:1 | ||||
| 9. Jornada | 04.03.2019 | Libertad | - | San Lorenzo | 2:1 |  |
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| 10. Jornada | 08.03.2019 | San Lorenzo | - | Deportivo Capiatá | 0:1 | ||||
| 11. Jornada | 18.03.2019 | General Díaz | - | San Lorenzo | 3:3 | ||||
| 13. Jornada | 31.03.2019 | San Lorenzo | - | Club Olimpia | 1:4 | ||||
| 14. Jornada | 05.04.2019 | Club Nacional | - | San Lorenzo | 3:1 | ||||
| 15. Jornada | 09.04.2019 | Guaraní | - | San Lorenzo | 4:1 | ||||
| 16. Jornada | 13.04.2019 | San Lorenzo | - | Sportivo Luqueño | 0:3 | ||||
| 17. Jornada | 21.04.2019 | Deportivo Santaní | - | San Lorenzo | 1:0 |  |
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| 18. Jornada | 26.04.2019 | San Lorenzo | - | Sol de América | 2:4 |
Paraguay