| 1. Jornada | 22.08.2010 | Liverpool | - | Rampla Juniors | 3:1 |  |
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| 2. Jornada | 29.08.2010 | Defensor Sporting | - | Liverpool | 3:0 | ||||
| 3. Jornada | 05.09.2010 | Liverpool | - | Racing | 1:0 | ||||
| 4. Jornada | 19.09.2010 | Tacuarembó | - | Liverpool | 3:2 | |
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| 5. Jornada | 26.09.2010 | Liverpool | - | Danubio | 1:1 | ||||
| 6. Jornada | 03.10.2010 | Nacional | - | Liverpool | 0:0 | ||||
| 7. Jornada | 09.10.2010 | Liverpool | - | Central Español | 2:2 | |
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| 8. Jornada | 17.10.2010 | Liverpool | - | Bella Vista | 1:1 | ||||
| 9. Jornada | 24.10.2010 | River Plate | - | Liverpool | 1:2 | |
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| 10. Jornada | 31.10.2010 | Peñarol | - | Liverpool | 1:2 | ||||
| 11. Jornada | 07.11.2010 | El Tanque Sisley | - | Liverpool | 1:1 | |
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| 12. Jornada | 14.11.2010 | Liverpool | - | Fénix | 2:1 | |
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| 13. Jornada | 21.11.2010 | Liverpool | - | Miramar Misiones | 0:0 | ||||
| 14. Jornada | 28.11.2010 | Liverpool | - | Montevideo Wanderers | 0:2 |
Uruguay
