| 2. Jornada | 10.07.2022 | Club León [Sub 20] | - | Pumas UNAM [Sub 20] | 3:2 | ||||
| 6. Jornada | 30.07.2022 | Pumas UNAM [Sub 20] | - | CF Monterrey [Sub 20] | 2:0 |  |
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| 8. Jornada | 13.08.2022 | Pumas UNAM [Sub 20] | - | CF América [Sub 20] | 1:1 | ||||
| 9. Jornada | 18.08.2022 | Atlético San Luis [Sub 20] | - | Pumas UNAM [Sub 20] | 0:2 | ||||
| 12. Jornada | 03.09.2022 | Atlas Guadalajara [Sub 20] | - | Pumas UNAM [Sub 20] | 1:0 |  |
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| 13. Jornada | 07.09.2022 | Pumas UNAM [Sub 20] | - | Gallos Blancos [Sub 20] | 2:0 | ||||
| 14. Jornada | 10.09.2022 | Deportivo Toluca [Sub 20] | - | Pumas UNAM [Sub 20] | 1:2 | |
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| 15. Jornada | 18.09.2022 | Pumas UNAM [Sub 20] | - | Cruz Azul [Sub 20] | 2:0 | |
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| 17. Jornada | 30.09.2022 | FC Juárez [Sub 20] | - | Pumas UNAM [Sub 20] | 3:0 |
México