| 1. Jornada | 25.07.2010 | Monarcas Morelia | - | Atlas Guadalajara | 1:0 |  |
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| 3. Jornada | 08.08.2010 | Atlas Guadalajara | - | Club Necaxa | 0:1 | ||||
| 5. Jornada | 22.08.2010 | Atlas Guadalajara | - | Deportivo Toluca | 0:1 |  |
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| 6. Jornada | 29.08.2010 | Santos Laguna | - | Atlas Guadalajara | 3:1 | |
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| 7. Jornada | 12.09.2010 | Atlas Guadalajara | - | Cruz Azul | 1:3 | ||||
| 8. Jornada | 19.09.2010 | CF Monterrey | - | Atlas Guadalajara | 2:0 | ||||
| 9. Jornada | 26.09.2010 | Atlas Guadalajara | - | Puebla FC | 1:0 | ||||
| 10. Jornada | 03.10.2010 | Deportivo Guadalajara | - | Atlas Guadalajara | 2:2 | ||||
| 12. Jornada | 16.10.2010 | Estudiantes Tecos | - | Atlas Guadalajara | 2:1 | |
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| 14. Jornada | 27.10.2010 | Pumas UNAM | - | Atlas Guadalajara | 1:1 | |
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| 15. Jornada | 31.10.2010 | Atlas Guadalajara | - | CF Pachuca | 1:2 | ||||
| 16. Jornada | 07.11.2010 | Jaguares Chiapas | - | Atlas Guadalajara | 2:1 | ||||
| 17. Jornada | 14.11.2010 | Atlas Guadalajara | - | UANL Tigres | 2:2 |  |
Paraguay