| 7. Jornada | 11.03.2023 | Libertad | - | Guaireña FC | 2:0 | ||||
| 9. Jornada | 24.03.2023 | Guaraní | - | Guaireña FC | 1:1 | ||||
| 10. Jornada | 02.04.2023 | Guaireña FC | - | Resistencia SC | 1:3 |  |
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| 11. Jornada | 09.04.2023 | Sportivo Luqueño | - | Guaireña FC | 0:0 | ||||
| 12. Jornada | 12.04.2023 | Club Nacional | - | Guaireña FC | 2:2 | ||||
| 13. Jornada | 15.04.2023 | Guaireña FC | - | Tacuary | 0:1 | ||||
| 17. Jornada | 12.05.2023 | General Caballero DJLM | - | Guaireña FC | 3:0 | ||||
| 18. Jornada | 17.05.2023 | Guaireña FC | - | Libertad | 0:2 | ||||
| 19. Jornada | 22.05.2023 | Sportivo Ameliano | - | Guaireña FC | 1:1 | ||||
| 20. Jornada | 29.05.2023 | Guaireña FC | - | Guaraní | 2:2 | ||||
| 21. Jornada | 04.06.2023 | Resistencia SC | - | Guaireña FC | 0:2 | ||||
| 22. Jornada | 09.06.2023 | Guaireña FC | - | Sportivo Luqueño | 0:2 |
Paraguay