| 1. Jornada | 03.07.2022 | Club Necaxa | - | Deportivo Toluca | 1:3 | ||||
| 2. Jornada | 11.07.2022 | Gallos Blancos | - | Club Necaxa | 1:2 | ||||
| 3. Jornada | 17.07.2022 | Pumas UNAM | - | Club Necaxa | 1:0 | ||||
| 4. Jornada | 23.07.2022 | Club Necaxa | - | FC Juárez | 1:0 |  |
|||
| 5. Jornada | 28.07.2022 | Club Necaxa | - | CF Pachuca | 2:0 | ||||
| 6. Jornada | 31.07.2022 | Cruz Azul | - | Club Necaxa | 1:0 | ||||
| 7. Jornada | 07.08.2022 | Atlético San Luis | - | Club Necaxa | 1:2 | |
|||
| 8. Jornada | 13.08.2022 | Club Necaxa | - | CF Monterrey | 1:2 | ||||
| 9. Jornada | 17.08.2022 | Puebla FC | - | Club Necaxa | 2:2 | |
|||
| 10. Jornada | 20.08.2022 | Club Necaxa | - | Deportivo Guadalajara | 0:4 | ||||
| 11. Jornada | 28.08.2022 | UANL Tigres | - | Club Necaxa | 0:0 | ||||
| 12. Jornada | 03.09.2022 | Club Necaxa | - | Club León | 3:2 | |
|||
| 13. Jornada | 07.09.2022 | Santos Laguna | - | Club Necaxa | 3:1 | ||||
| 14. Jornada | 11.09.2022 | Club Necaxa | - | CF América | 1:2 | |
|||
| 15. Jornada | 19.09.2022 | Club Tijuana | - | Club Necaxa | 1:1 | ||||
| 16. Jornada | 24.09.2022 | Club Necaxa | - | Mazatlán FC | 2:2 | |
 |
||
| 17. Jornada | 02.10.2022 | Atlas Guadalajara | - | Club Necaxa | 1:0 |
Uruguay