| 5. Jornada | 29.08.2021 | Sacramento Republic | - | San Diego Loyal | 1:3 | ||||
| 6. Jornada | 06.09.2021 | San Diego Loyal | - | Los Angeles Galaxy II | 4:2 | ||||
| 6. Jornada | 12.09.2021 | Oakland Roots | - | San Diego Loyal | 0:0 |  |
|||
| 7. Jornada | 03.10.2021 | Los Angeles Galaxy II | - | San Diego Loyal | 0:3 | ||||
| 7. Jornada | 10.10.2021 | San Diego Loyal | - | Sacramento Republic | 2:1 | ||||
| 7. Jornada | 25.10.2021 | San Diego Loyal | - | Oakland Roots | 3:4 |
Canadá