| 1. Jornada | 13.03.2010 | FK Rostov | - | FK Tom Tomsk | 0:2 | ||||
| 2. Jornada | 22.03.2010 | FK Tom Tomsk | - | Rubin Kazan | 0:1 | ||||
| 3. Jornada | 27.03.2010 | Krylia Sovetov | - | FK Tom Tomsk | 2:3 | ||||
| 4. Jornada | 04.04.2010 | FK Tom Tomsk | - | Spartak Moskva | 2:2 | ||||
| 6. Jornada | 17.04.2010 | FK Tom Tomsk | - | Zenit | 0:0 | ||||
| 7. Jornada | 24.04.2010 | Lokomotiv Moskva | - | FK Tom Tomsk | 2:1 | ||||
| 12. Jornada | 10.07.2010 | FK Amkar Perm | - | FK Tom Tomsk | 2:1 | ||||
| 13. Jornada | 18.07.2010 | FK Tom Tomsk | - | Anzhi Makhachkala | 1:4 | ||||
| 14. Jornada | 24.07.2010 | Spartak Vladikavkaz | - | FK Tom Tomsk | 2:1 | ||||
| 15. Jornada | 02.08.2010 | FK Tom Tomsk | - | Sibir Novosibirsk | 3:2 | ||||
| 17. Jornada | 14.08.2010 | FK Tom Tomsk | - | Krylia Sovetov | 1:1 | ||||
| 18. Jornada | 21.08.2010 | Spartak Moskva | - | FK Tom Tomsk | 4:2 | ||||
| 20. Jornada | 11.09.2010 | Zenit | - | FK Tom Tomsk | 2:0 | ||||
| 22. Jornada | 26.09.2010 | FK Tom Tomsk | - | CSKA Moscú | 0:3 | ||||
| 23. Jornada | 02.10.2010 | Terek Grozny | - | FK Tom Tomsk | 1:0 | ||||
| 24. Jornada | 16.10.2010 | FK Tom Tomsk | - | FK Saturn | 2:2 | ||||
| 27. Jornada | 06.11.2010 | Anzhi Makhachkala | - | FK Tom Tomsk | 1:0 |
Macedonia del Norte