| Eliminatoria previa | 09.03.2022 | Liverpool | - | River Plate | 0:1 |  |
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| Eliminatoria previa | 16.03.2022 | River Plate | - | Liverpool | 2:0 | |
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| Grupo B | 08.04.2022 | River Plate | - | Racing Club | 0:1 | ||||
| Grupo B | 14.04.2022 | FBC Melgar | - | River Plate | 2:0 | ||||
| Grupo B | 28.04.2022 | Cuiabá - MT | - | River Plate | 1:2 |  |
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| Grupo B | 19.05.2022 | River Plate | - | Cuiabá - MT | 1:2 | ||||
| Grupo B | 27.05.2022 | Racing Club | - | River Plate | 0:1 | |
Uruguay
Ecuador 