| Eliminatoria previa | 18.03.2022 | Cerro Largo | - | Montevideo Wanderers | 0:1 | ||||
| Grupo A | 08.04.2022 | Barcelona | - | Montevideo Wanderers | 4:2 | ||||
| Grupo A | 15.04.2022 | Montevideo Wanderers | - | Metropolitanos FC | 1:1 | ||||
| Grupo A | 05.05.2022 | Metropolitanos FC | - | Montevideo Wanderers | 0:1 |  |
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| Grupo A | 26.05.2022 | Montevideo Wanderers | - | Barcelona | 0:0 |
Uruguay