| 7. Jornada | 22.02.2021 | CF Pachuca [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 3:2 | ||||
| 8. Jornada | 28.02.2021 | Deportivo Guadalajara [Sub 20] | - | Pumas UNAM [Sub 20] | 1:2 | ||||
| 9. Jornada | 03.03.2021 | Gallos Blancos [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 1:0 | ||||
| 12. Jornada | 20.03.2021 | CF Monterrey [Sub 20] | - | Deportivo Guadalajara [Sub 20] | 1:0 | ||||
| 13. Jornada | 04.04.2021 | Deportivo Guadalajara [Sub 20] | - | Santos Laguna [Sub 20] | 5:2 | ||||
| 15. Jornada | 17.04.2021 | Deportivo Guadalajara [Sub 20] | - | Club Tijuana [Sub 20] | 2:1 | ||||
| 17. Jornada | 01.05.2021 | Deportivo Guadalajara [Sub 20] | - | UANL Tigres [Sub 20] | 1:1 |
México