| 1. Jornada | 08.07.2022 | Patriotas FC | - | Atlético Junior | 1:0 |  |
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| 2. Jornada | 14.07.2022 | Atlético Junior | - | Atlético Nacional | 3:1 | ||||
| 3. Jornada | 17.07.2022 | La Equidad | - | Atlético Junior | 0:0 | ||||
| 5. Jornada | 31.07.2022 | Águilas Doradas | - | Atlético Junior | 1:1 | |
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| 6. Jornada | 08.08.2022 | Atlético Junior | - | Once Caldas | 1:2 | |
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| 7. Jornada | 14.08.2022 | Atlético Junior | - | Independiente Medellín | 4:2 | ||||
| 8. Jornada | 21.08.2022 | América de Cali | - | Atlético Junior | 2:1 | ||||
| 9. Jornada | 29.08.2022 | Atlético Junior | - | Deportes Tolima | 2:1 | ||||
| 10. Jornada | 04.09.2022 | Unión Magdalena | - | Atlético Junior | 2:1 | ||||
| 11. Jornada | 10.09.2022 | Atlético Junior | - | Deportivo Pereira | 0:0 | |
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| 12. Jornada | 18.09.2022 | Deportivo Pasto | - | Atlético Junior | 2:1 | |
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| 14. Jornada | 26.09.2022 | Alianza Petrolera | - | Atlético Junior | 0:1 | |
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| 20. Jornada | 30.10.2022 | Jaguares de Córdoba | - | Atlético Junior | 0:2 |
Colombia