| 1. Jornada | 25.06.2022 | Pumas UNAM [] | - | Cruz Azul [] | 3:2 | ||||
| 2. Jornada | 02.07.2022 | Gallos Blancos [] | - | Pumas UNAM [] | 1:2 | ||||
| 9. Jornada | 20.08.2022 | Puebla FC [] | - | Pumas UNAM [] | 1:2 | ||||
| 10. Jornada | 27.08.2022 | Cruz Azul [] | - | Pumas UNAM [] | 0:4 | ||||
| 11. Jornada | 03.09.2022 | Pumas UNAM [] | - | Gallos Blancos [] | 3:0 | ||||
| 12. Jornada | 10.09.2022 | Deportivo Toluca [] | - | Pumas UNAM [] | 1:0 | ||||
| 13. Jornada | 17.09.2022 | Pumas UNAM [] | - | Club Necaxa [] | 2:1 | ||||
| 15. Jornada | 01.10.2022 | CF Pachuca [] | - | Pumas UNAM [] | 3:3 | ||||
| 18. Jornada | 22.10.2022 | Pumas UNAM [] | - | Puebla FC [] | 1:0 |  |
México