| 1. Jornada | 06.01.2022 | Atlético San Luis [Sub 20] | - | CF Pachuca [Sub 20] | 0:2 | ||||
| 5. Jornada | 12.02.2022 | Atlético San Luis [Sub 20] | - | Deportivo Toluca [Sub 20] | 4:1 | ||||
| 7. Jornada | 26.02.2022 | CF Monterrey [Sub 20] | - | Atlético San Luis [Sub 20] | 1:3 | ||||
| 10. Jornada | 13.03.2022 | Atlético San Luis [Sub 20] | - | Puebla FC [Sub 20] | 3:1 |
México