| 1. Jornada | 08.01.2022 | Deportivo Guadalajara [Sub 16] | - | Atlético San Luis [Sub 16] | 1:1 | ||||
| 2. Jornada | 16.01.2022 | Atlético San Luis [Sub 16] | - | Mazatlán FC [Sub 16] | 1:2 | ||||
| 6. Jornada | 12.02.2022 | Club León [Sub 16] | - | Atlético San Luis [Sub 16] | 2:1 | ||||
| 13. Jornada | 02.04.2022 | UANL Tigres [Sub 16] | - | Atlético San Luis [Sub 16] | 2:1 | ||||
| 16. Jornada | 23.04.2022 | Mazatlán FC [Sub 16] | - | Atlético San Luis [Sub 16] | 2:1 | ||||
| 18. Jornada | 07.05.2022 | Atlas Guadalajara [Sub 16] | - | Atlético San Luis [Sub 16] | 4:2 |
México