| 5. Jornada | 15.02.2025 | Club Nacional | - | Guaraní | 1:2 | ||||
| 9. Jornada | 14.03.2025 | Guaraní | - | Atlético Tembetary | 0:0 | ||||
| 14. Jornada | 16.04.2025 | Guaraní | - | 2 de Mayo | 0:1 | ||||
| 15. Jornada | 19.04.2025 | Libertad | - | Guaraní | 1:3 | ||||
| 16. Jornada | 27.04.2025 | Guaraní | - | Club Nacional | 2:1 | ||||
| 18. Jornada | 10.05.2025 | Guaraní | - | Cerro Porteño | 0:2 | ||||
| 20. Jornada | 22.05.2025 | Atlético Tembetary | - | Guaraní | 1:2 | ||||
| 21. Jornada | 25.05.2025 | Guaraní | - | Sportivo Luqueño | 2:1 |
Paraguay