| 5. Jornada | 31.07.2010 | Philadelphia Union | - | New England Revolution | 1:1 | ||||
| 6. Jornada | 06.08.2010 | Philadelphia Union | - | Columbus Crew | 1:2 | ||||
| 6. Jornada | 09.08.2010 | FC Dallas | - | Philadelphia Union | 3:1 | ||||
| 6. Jornada | 12.08.2010 | Philadelphia Union | - | Real Salt Lake | 1:1 | ||||
| 6. Jornada | 14.08.2010 | Philadelphia Union | - | Colorado Rapids | 1:1 | ||||
| 6. Jornada | 22.08.2010 | D.C. United | - | Philadelphia Union | 2:0 | ||||
| 6. Jornada | 29.08.2010 | New England Revolution | - | Philadelphia Union | 1:2 |  |
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| 7. Jornada | 04.09.2010 | Philadelphia Union | - | Kansas City Wizards | 1:1 | ||||
| 7. Jornada | 12.09.2010 | Philadelphia Union | - | Chicago Fire | 1:0 | ||||
| 7. Jornada | 16.09.2010 | San Jose Earthquakes | - | Philadelphia Union | 1:0 | ||||
| 7. Jornada | 25.09.2010 | Philadelphia Union | - | CD Chivas | 3:0 |  |
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| 7. Jornada | 30.09.2010 | Colorado Rapids | - | Philadelphia Union | 4:1 | ||||
| 8. Jornada | 08.10.2010 | Philadelphia Union | - | Los Angeles Galaxy | 0:1 | ||||
| 8. Jornada | 17.10.2010 | Philadelphia Union | - | New York RB | 2:1 | ||||
| 8. Jornada | 24.10.2010 | Columbus Crew | - | Philadelphia Union | 3:1 |
Estados Unidos