| 1. Jornada | 16.07.2021 | Independiente II | - | Argentinos Juniors II | 3:0 | ||||
| 2. Jornada | 23.07.2021 | Argentinos Juniors II | - | Newell's Old Boys II | 3:1 | ||||
| 3. Jornada | 27.07.2021 | Arsenal de Sarandí II | - | Argentinos Juniors II | 3:1 | ||||
| 4. Jornada | 02.08.2021 | Argentinos Juniors II | - | Central Córdoba SdE II | 1:0 | ||||
| 7. Jornada | 20.08.2021 | San Lorenzo II | - | Argentinos Juniors II | 1:3 | ||||
| 8. Jornada | 26.08.2021 | Argentinos Juniors II | - | Talleres de Córdoba II | 0:1 | ||||
| 9. Jornada | 30.08.2021 | Unión de Santa Fe II | - | Argentinos Juniors II | 1:2 | ||||
| 10. Jornada | 03.09.2021 | Estudiantes II | - | Argentinos Juniors II | 2:0 | ||||
| 16. Jornada | 17.10.2021 | Atlético Tucumán II | - | Argentinos Juniors II | 0:0 | ||||
| 17. Jornada | 21.10.2021 | Argentinos Juniors II | - | Colón de Santa Fe II | 2:1 | ||||
| 18. Jornada | 26.10.2021 | River Plate II | - | Argentinos Juniors II | 0:3 | ||||
| 19. Jornada | 01.11.2021 | Argentinos Juniors II | - | Lanús II | 2:1 | ||||
| 20. Jornada | 09.11.2021 | Huracán II | - | Argentinos Juniors II | 1:0 |
Argentina