| 4. Jornada | 28.08.2021 | AS Saint-Priest | - | Lyon (CFA) | 1:3 | ||||
| 6. Jornada | 11.09.2021 | GOAL FC | - | Lyon (CFA) | 2:0 | ||||
| 7. Jornada | 18.09.2021 | Lyon (CFA) | - | Aubagne FC | 3:1 | ||||
| 8. Jornada | 25.09.2021 | Jura Sud | - | Lyon (CFA) | 1:1 | ||||
| 10. Jornada | 23.10.2021 | Marignane Gignac FC | - | Lyon (CFA) | 4:0 | ||||
| 11. Jornada | 06.11.2021 | Lyon (CFA) | - | SC Toulon | 0:0 |  |
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| 17. Jornada | 05.02.2022 | GFA Rumilly Vallières | - | Lyon (CFA) | 0:0 | ||||
| 18. Jornada | 12.02.2022 | Lyon (CFA) | - | AS Saint-Priest | 0:0 | ||||
| 21. Jornada | 12.03.2022 | Aubagne FC | - | Lyon (CFA) | 3:0 | |
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| 24. Jornada | 09.04.2022 | Lyon (CFA) | - | Marignane Gignac FC | 3:1 | ||||
| 25. Jornada | 16.04.2022 | SC Toulon | - | Lyon (CFA) | 2:1 | ||||
| 26. Jornada | 23.04.2022 | RC Grasse | - | Lyon (CFA) | 2:1 | ||||
| 28. Jornada | 14.05.2022 | Hyères FC | - | Lyon (CFA) | 1:1 |
Francia