| 1. Jornada | 23.01.2019 | Sol de América | - | Libertad | 2:0 | ||||
| 2. Jornada | 27.01.2019 | Libertad | - | Cerro Porteño | 1:0 | ||||
| 3. Jornada | 02.02.2019 | Guaraní | - | Libertad | 3:1 | ||||
| 5. Jornada | 09.02.2019 | Libertad | - | General Díaz | 4:0 | ||||
| 6. Jornada | 17.02.2019 | River Plate | - | Libertad | 1:1 | ||||
| 7. Jornada | 24.02.2019 | Libertad | - | Club Olimpia | 2:3 | ||||
| 10. Jornada | 10.03.2019 | Sportivo Luqueño | - | Libertad | 2:2 |  |
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| 13. Jornada | 30.03.2019 | Cerro Porteño | - | Libertad | 1:2 | ||||
| 16. Jornada | 14.04.2019 | General Díaz | - | Libertad | 1:3 | ||||
| 14. Jornada | 18.04.2019 | Libertad | - | Guaraní | 1:1 | ||||
| 17. Jornada | 21.04.2019 | Libertad | - | River Plate | 2:1 | ||||
| 18. Jornada | 28.04.2019 | Club Olimpia | - | Libertad | 3:0 | ||||
| 19. Jornada | 03.05.2019 | Libertad | - | Club Nacional | 1:2 | ||||
| 20. Jornada | 06.05.2019 | San Lorenzo | - | Libertad | 3:4 | ||||
| 21. Jornada | 12.05.2019 | Libertad | - | Sportivo Luqueño | 1:0 | ||||
| 22. Jornada | 18.05.2019 | Deportivo Santaní | - | Libertad | 0:3 |
Uruguay