| 1. Jornada | 25.06.2022 | Atlético San Luis [] | - | CF Monterrey [] | 0:5 | ||||
| 6. Jornada | 30.07.2022 | Atlético San Luis [] | - | UANL Tigres [] | 1:4 | ||||
| 10. Jornada | 27.08.2022 | CF Monterrey [] | - | Atlético San Luis [] | 5:1 | ||||
| 11. Jornada | 03.09.2022 | Atlético San Luis [] | - | Club Tijuana [] | 0:2 | ||||
| 12. Jornada | 11.09.2022 | Deportivo Guadalajara [] | - | Atlético San Luis [] | 3:1 | ||||
| 13. Jornada | 18.09.2022 | Atlético San Luis [] | - | Club León [] | 0:4 | ||||
| 14. Jornada | 24.09.2022 | UANL Tigres [] | - | Atlético San Luis [] | 5:2 | ||||
| 15. Jornada | 02.10.2022 | Atlético San Luis [] | - | Atlas Guadalajara [] | 0:3 | ||||
| 16. Jornada | 08.10.2022 | Santos Laguna [] | - | Atlético San Luis [] | 4:0 | ||||
| 17. Jornada | 15.10.2022 | Atlético San Luis [] | - | Mazatlán FC [] | 2:2 |
México