| 2. Jornada | 01.08.2021 | FC Vaduz | - | Neuchâtel Xamax FCS | 1:2 | ||||
| 3. Jornada | 06.08.2021 | Neuchâtel Xamax FCS | - | SC Kriens | 4:0 | ||||
| 1. Jornada | 10.08.2021 | Neuchâtel Xamax FCS | - | FC Aarau | 4:2 | ||||
| 4. Jornada | 21.08.2021 | Yverdon Sport FC | - | Neuchâtel Xamax FCS | 1:1 | ||||
| 9. Jornada | 01.10.2021 | FC Schaffhausen | - | Neuchâtel Xamax FCS | 4:0 | ||||
| 10. Jornada | 15.10.2021 | Neuchâtel Xamax FCS | - | FC Vaduz | 0:2 | ||||
| 11. Jornada | 22.10.2021 | FC Wil 1900 | - | Neuchâtel Xamax FCS | 2:1 | ||||
| 12. Jornada | 29.10.2021 | Neuchâtel Xamax FCS | - | FC Winterthur | 1:1 |  |
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| 14. Jornada | 20.11.2021 | SC Kriens | - | Neuchâtel Xamax FCS | 0:1 | ||||
| 18. Jornada | 17.12.2021 | FC Aarau | - | Neuchâtel Xamax FCS | 1:0 | ||||
| 23. Jornada | 25.02.2022 | Neuchâtel Xamax FCS | - | SC Kriens | 2:1 | ||||
| 24. Jornada | 01.03.2022 | FC Thun | - | Neuchâtel Xamax FCS | 1:2 | ||||
| 25. Jornada | 04.03.2022 | Neuchâtel Xamax FCS | - | FC Vaduz | 2:4 | ||||
| 26. Jornada | 12.03.2022 | FC Wil 1900 | - | Neuchâtel Xamax FCS | 2:0 | ||||
| 36. Jornada | 21.05.2022 | Neuchâtel Xamax FCS | - | FC Wil 1900 | 5:2 |
Francia
Portugal