| 1. Jornada | 22.07.2012 | Santos Laguna | - | Club San Luis | 2:1 | ||||
| 2. Jornada | 29.07.2012 | Club San Luis | - | Cruz Azul | 1:2 |  |
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| 3. Jornada | 04.08.2012 | Monarcas Morelia | - | Club San Luis | 3:3 | ||||
| 4. Jornada | 12.08.2012 | Club San Luis | - | CF Monterrey | 1:1 | ||||
| 5. Jornada | 19.08.2012 | Club San Luis | - | Deportivo Guadalajara | 0:1 |  |
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| 6. Jornada | 26.08.2012 | Puebla FC | - | Club San Luis | 1:0 | ||||
| 9. Jornada | 23.09.2012 | Club San Luis | - | CF Pachuca | 1:0 | ||||
| 10. Jornada | 30.09.2012 | UANL Tigres | - | Club San Luis | 0:0 | ||||
| 12. Jornada | 08.10.2012 | Jaguares Chiapas | - | Club San Luis | 4:0 | ||||
| 13. Jornada | 14.10.2012 | Club San Luis | - | Atlante | 2:2 |
Estados Unidos
México