| 1. Jornada | 02.07.2022 | Mazatlán FC | - | Puebla FC | 2:4 | ||||
| 2. Jornada | 09.07.2022 | Mazatlán FC | - | UANL Tigres | 0:1 |  |
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| 6. Jornada | 31.07.2022 | Club Tijuana | - | Mazatlán FC | 2:0 | ||||
| 9. Jornada | 17.08.2022 | Mazatlán FC | - | Gallos Blancos | 1:1 | ||||
| 10. Jornada | 21.08.2022 | FC Juárez | - | Mazatlán FC | 1:1 | ||||
| 13. Jornada | 08.09.2022 | Mazatlán FC | - | Atlas Guadalajara | 1:0 | ||||
| 15. Jornada | 17.09.2022 | Mazatlán FC | - | Deportivo Toluca | 1:1 | ||||
| 16. Jornada | 24.09.2022 | Club Necaxa | - | Mazatlán FC | 2:2 |  |
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| 17. Jornada | 03.10.2022 | Santos Laguna | - | Mazatlán FC | 3:0 | |
México