| 3. Jornada | 12.09.2021 | Balzan FC | - | Birkirkara FC | 1:2 | ||||
| 5. Jornada | 26.09.2021 | Mosta FC | - | Balzan FC | 2:1 |  |
|||
| 6. Jornada | 16.10.2021 | Balzan FC | - | Floriana FC | 1:2 | |
|||
| 7. Jornada | 23.10.2021 | Gżira United | - | Balzan FC | 1:2 | ||||
| 8. Jornada | 31.10.2021 | Balzan FC | - | Gudja United | 1:0 | ||||
| 9. Jornada | 21.11.2021 | Sirens FC | - | Balzan FC | 1:6 | |
|||
| 11. Jornada | 05.12.2021 | St. Luċija FC | - | Balzan FC | 3:3 | ||||
| 13. Jornada | 19.12.2021 | Balzan FC | - | Valletta FC | 2:1 | ||||
| 14. Jornada | 19.01.2022 | Birkirkara FC | - | Balzan FC | 3:2 | ||||
| 12. Jornada | 26.01.2022 | Sliema Wanderers | - | Balzan FC | 1:0 | ||||
| 16. Jornada | 29.01.2022 | Balzan FC | - | Mosta FC | 2:3 | ||||
| 18. Jornada | 12.02.2022 | Balzan FC | - | Gżira United | 1:3 | ||||
| 19. Jornada | 19.02.2022 | Gudja United | - | Balzan FC | 1:0 | ||||
| 20. Jornada | 27.02.2022 | Balzan FC | - | Sirens FC | 2:1 | ||||
| 21. Jornada | 05.03.2022 | Hibernians FC | - | Balzan FC | 1:0 | ||||
| 22. Jornada | 11.03.2022 | Balzan FC | - | St. Luċija FC | 0:1 |
Malta