| 1. Jornada | 11.02.2022 | Sarmiento de Junín II | - | Atlético Tucumán II | 2:1 | ||||
| 5. Jornada | 04.03.2022 | Newell's Old Boys II | - | Atlético Tucumán II | 2:3 | ||||
| 6. Jornada | 14.03.2022 | Atlético Tucumán II | - | Racing Club II | 2:6 | ||||
| 7. Jornada | 21.03.2022 | Atlético Tucumán II | - | Central Córdoba SdE II | 2:2 |  |
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| 8. Jornada | 04.04.2022 | San Lorenzo II | - | Atlético Tucumán II | 1:1 | ||||
| 9. Jornada | 11.04.2022 | Atlético Tucumán II | - | Gimnasia de La Plata II | 3:2 | ||||
| 10. Jornada | 15.04.2022 | Defensa y Justicia II | - | Atlético Tucumán II | 1:0 | ||||
| 11. Jornada | 21.04.2022 | Atlético Tucumán II | - | Argentinos Juniors II | 2:1 | ||||
| 12. Jornada | 25.04.2022 | River Plate II | - | Atlético Tucumán II | 4:0 | ||||
| 14. Jornada | 06.05.2022 | Banfield II | - | Atlético Tucumán II | 3:4 | |
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Argentina