| 1. Jornada | 20.07.2001 | Puebla FC | - | Club Necaxa | 1:1 | ||||
| 2. Jornada | 28.07.2001 | CF Pachuca | - | Puebla FC | 0:3 |  |
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| 3. Jornada | 03.08.2001 | Puebla FC | - | Deportivo Toluca | 0:0 | ||||
| 4. Jornada | 10.08.2001 | UANL Tigres | - | Puebla FC | 2:0 |  |
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| 5. Jornada | 14.08.2001 | Puebla FC | - | CF Monterrey | 2:1 | ||||
| 6. Jornada | 18.08.2001 | Club Irapuato | - | Puebla FC | 2:3 | ||||
| 7. Jornada | 24.08.2001 | Puebla FC | - | Atletico Celaya | 1:1 | ||||
| 8. Jornada | 07.09.2001 | Atlas Guadalajara | - | Puebla FC | 3:1 | ||||
| 9. Jornada | 14.09.2001 | Puebla FC | - | Deportivo Guadalajara | 1:1 | ||||
| 11. Jornada | 28.09.2001 | Puebla FC | - | UAG Tecos | 1:1 | ||||
| 12. Jornada | 06.10.2001 | Reboceros de la Piedad | - | Puebla FC | 3:2 | |
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| 13. Jornada | 13.10.2001 | Puebla FC | - | Santos Laguna | 2:1 | ||||
| 15. Jornada | 26.10.2001 | Puebla FC | - | Atlante | 0:0 | ||||
| 19. Jornada | 24.11.2001 | CF América | - | Puebla FC | 1:0 |
Paraguay