| 5. Jornada | 22.07.2018 | Columbus Crew | - | Orlando City | 3:2 | ||||
| 5. Jornada | 29.07.2018 | New York RB | - | Columbus Crew | 2:3 |  |
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| 6. Jornada | 12.08.2018 | Columbus Crew | - | Houston Dynamo | 1:0 | ||||
| 6. Jornada | 19.08.2018 | Atlanta United FC | - | Columbus Crew | 3:1 | ||||
| 6. Jornada | 24.08.2018 | Chicago Fire | - | Columbus Crew | 1:1 | ||||
| 7. Jornada | 16.09.2018 | FC Dallas | - | Columbus Crew | 0:0 | ||||
| 7. Jornada | 20.09.2018 | Portland Timbers | - | Columbus Crew | 3:2 | ||||
| 8. Jornada | 06.10.2018 | Impact de Montréal | - | Columbus Crew | 3:0 | ||||
| 8. Jornada | 21.10.2018 | Orlando City | - | Columbus Crew | 2:1 | ||||
| 8. Jornada | 28.10.2018 | Columbus Crew | - | Minnesota United FC | 3:2 |
Estados Unidos