| 8. Jornada | 13.09.2021 | CF Pachuca [Sub 18] | - | Deportivo Toluca [Sub 18] | 2:2 |  |
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| 9. Jornada | 18.09.2021 | Deportivo Guadalajara [Sub 18] | - | CF Pachuca [Sub 18] | 0:4 | |
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| 10. Jornada | 23.09.2021 | CF Pachuca [Sub 18] | - | Club Necaxa [Sub 18] | 5:1 | |
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| 11. Jornada | 28.09.2021 | CF Pachuca [Sub 18] | - | CF América [Sub 18] | 4:1 | |
México