| 2. Jornada | 15.01.2022 | Deportivo Toluca [] | - | Club Necaxa [] | 2:1 | ||||
| 3. Jornada | 22.01.2022 | Club Necaxa [] | - | Cruz Azul [] | 4:1 |  |
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| 4. Jornada | 29.01.2022 | FC Juárez [] | - | Club Necaxa [] | 1:0 | ||||
| 5. Jornada | 05.02.2022 | Club Necaxa [] | - | Puebla FC [] | 4:0 | ||||
| 6. Jornada | 12.02.2022 | Club Necaxa [] | - | CF Pachuca [] | 2:1 | ||||
| 7. Jornada | 19.02.2022 | CF América [] | - | Club Necaxa [] | 3:3 | ||||
| 8. Jornada | 26.02.2022 | Club Necaxa [] | - | Gallos Blancos [] | 3:1 |
México