| 5. Jornada | 19.08.2019 | Club Necaxa | - | Santos Laguna | 3:0 | ||||
| 6. Jornada | 24.08.2019 | Santos Laguna | - | CF Monterrey | 2:1 | ||||
| 10. Jornada | 22.09.2019 | Atlético San Luis | - | Santos Laguna | 2:3 | ||||
| 14. Jornada | 19.10.2019 | Santos Laguna | - | Club Tijuana | 4:1 |  |
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| 15. Jornada | 26.10.2019 | Monarcas Morelia | - | Santos Laguna | 2:2 | ||||
| 16. Jornada | 30.10.2019 | Santos Laguna | - | Gallos Blancos | 1:0 | ||||
| 17. Jornada | 03.11.2019 | CF América | - | Santos Laguna | 1:2 | ||||
| 18. Jornada | 11.11.2019 | Santos Laguna | - | Cruz Azul | 3:1 | |
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| 19. Jornada | 24.11.2019 | Deportivo Toluca | - | Santos Laguna | 2:2 |
Uruguay
España 