| 2. Jornada | 08.03.2023 | Club Nacional | - | Club Olimpia | 1:1 | ||||
| 7. Jornada | 13.03.2023 | Resistencia SC | - | Club Nacional | 0:1 | ||||
| 8. Jornada | 19.03.2023 | Club Nacional | - | Sportivo Luqueño | 0:1 | ||||
| 9. Jornada | 26.03.2023 | Cerro Porteño | - | Club Nacional | 4:1 |  |
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| 10. Jornada | 01.04.2023 | Tacuary | - | Club Nacional | 0:0 | ||||
| 11. Jornada | 08.04.2023 | Club Nacional | - | Sportivo Trinidense | 0:1 |  |
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| 12. Jornada | 12.04.2023 | Club Nacional | - | Guaireña FC | 2:2 | ||||
| 13. Jornada | 16.04.2023 | Club Olimpia | - | Club Nacional | 0:1 | ||||
| 14. Jornada | 24.04.2023 | Club Nacional | - | General Caballero DJLM | 2:0 | |
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| 15. Jornada | 29.04.2023 | Libertad | - | Club Nacional | 2:1 | ||||
| 16. Jornada | 06.05.2023 | Club Nacional | - | Sportivo Ameliano | 1:0 | |
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| 17. Jornada | 14.05.2023 | Guaraní | - | Club Nacional | 2:2 | |
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| 18. Jornada | 19.05.2023 | Club Nacional | - | Resistencia SC | 0:0 |
Paraguay