| 1. Jornada | 20.08.2021 | AEK Larnaca | - | Doxa Katokopias | 1:1 |  |
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| 4. Jornada | 24.09.2021 | Doxa Katokopias | - | Ethnikos Achna | 0:0 | ||||
| 5. Jornada | 02.10.2021 | Paphos FC | - | Doxa Katokopias | 1:1 | ||||
| 6. Jornada | 18.10.2021 | Doxa Katokopias | - | Aris Limassol | 1:2 | ||||
| 7. Jornada | 22.10.2021 | Olympiacos Nikosia | - | Doxa Katokopias | 1:0 | ||||
| 8. Jornada | 30.10.2021 | Doxa Katokopias | - | APOEL Nikosia | 2:2 |  |
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| 9. Jornada | 05.11.2021 | Apollon Limassol | - | Doxa Katokopias | 3:0 | ||||
| 10. Jornada | 21.11.2021 | Doxa Katokopias | - | AEL Limassol | 0:0 | |
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| 11. Jornada | 27.11.2021 | PAEEK | - | Doxa Katokopias | 1:2 | ||||
| 12. Jornada | 04.12.2021 | Doxa Katokopias | - | AEK Larnaca | 1:4 | ||||
| 13. Jornada | 13.12.2021 | Anorthosis Famagusta | - | Doxa Katokopias | 2:0 | |
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| 14. Jornada | 19.12.2021 | Doxa Katokopias | - | Omonia Nikosia | 2:1 | |
Guinea-Bissau
Portugal